Posts by author:

Brendan Penwarden

After far too much time and study it is still unclear which type of physical activity contributes the most to a reduction in cardiovascular disease. To attempt to resolve this 23,000 men and women from the general Dutch population were studied between 1993 and 1997. Remarkably, almost the entire study population (97%) was engaged in [...]

{ 0 comments }

Dose diet affect erectile function? Encouraging customers, especially men, to eat a healthier diet may have just got a bit easier. Epidemiological evidence now clearly supports a role for several dietary factors in the pathogenesis of erectile dysfunction. The prevalence of erectile dysfunction is surprisingly high. A review of general practice patients in Perth, Australia [...]

{ 1 comment }

Methylation is a mechanism we use to switch genes on and off. By attaching a methyl group to the nucleotide cytosine we silence that gene. Removing the methyl group allows the gene to be transcribed. Insufficient methylation raises the possbility that oncogenes will remain active leading to an increased risk to cancer. Now, too much [...]

{ 1 comment }

Nearly half of all adults in the US have at least one chronic health condition that increases their risk to the major cause of death, cardiovascular disease. The Centres for Disease Control and Prevention has found that  45% of all people aged 20 years or older have either hypertension, high cholesterol, diabetes, or some combination [...]

{ 0 comments }

They are worse off. We spoke in a previous post about the supra-additive effects of obesity on alcohol consumption. We found that obese people are at much higher risk to the damaging effects of alcohol because of their high fat mass. While alcohol may have some protective effect on stroke risk, any real effect is [...]

{ 0 comments }

Mental deterioration is slowed by engaging in tasks requiring mental agility. Computer use, which is a complex mental task, is one such activity that preserves cognitive function in elderly people. When we combine physical exercise with computer use we can produce a greater than additive effect to reduce brain ageing. . A number of studies [...]

{ 0 comments }

A women who gains too much weight during pregnancy places her children at high risk to future heart disease and obesity. Also, these mothers will themselves maintain a higher fat mass as they get older. The mother who gains excess weight will have a child with a higher BMI, waist circumference, fat mass, leptin, systolic [...]

{ 0 comments }

What is RSS? It is a very easy way to keep a watch for new material on websites, blogs, journal articles, newspapers, magazines – any on-line naterial. All of the changes to any of the above on-line media are collected and organised for you by an RSS Reader. Here is a screen shot of my [...]

{ 0 comments }

Here’s one we need to watch. Multivitamins during late pregnancy may contribute to prematurity. A study of pregnant women, 80% of whom took multivitamins at some point during their pregnancy, showed no effect on timing of birth. Those 30% however, who took them in the last trimester were three times more likely to be premature. [...]

{ 0 comments }

Obesity increases the toxicity of alcohol and together they dramatically increase liver disease. Cirrhosis of the liver and deaths from cirrhosis are increasing rapidly in both men and women. Although alcohol consumption has increased over the past 10 years, cirrhosis has increased even faster. The Million Women Study is following 1.3 million middle aged women [...]

{ 2 comments }

Post image for Blood pressure variability is the risk factor

Variability in blood pressure is a much stronger predictor of both stroke and coronary disease than average blood pressure alone. In fact, BP by itself has limited predictive power. Blood pressure variability within a clinic visit is more predictive than average pressure. The strongest indicator of future stroke or cardiovascular disease in the next five [...]

{ 0 comments }

Get gran Googling

by Brendan Penwarden on March 25, 2010

Post image for Get gran Googling

Recommending increased internet and computer usage for children is unlikely to be beneficial however may  be a strategy to preserve brain function and mood in your older patients. Only about 40% of people over 65 use the Internet and a substantial amount of benefit may be achieved by  increasing this percentage. Internet challenges the brain [...]

{ 0 comments }

A recent research article caught my eye and became the topic of this very interesting researcher interview for this post. The fundamental premise, contrary to the experience of many parents, is that children do not have an inbuilt disliking to foods, not even vegetables. They can be successfully introduced to a wide range of healthy [...]

{ 0 comments }

This morning I watched a TED talk. I had been recommended it and was reluctant to watch it as it was about online gaming. My nephews spent many hours playing online games when they were younger and of course I was the one to roll my eyes and tell them that there were more important [...]

{ 0 comments }

Post image for Anti-inflammatory drugs increase cancer risk

Some of the drugs used to treat Crohn’s disease and ulcerative colitis increase the risk of malignant lymphoproliferative disorders including leukaemia and myeloma. Azathioprine and  Mercaptopurine are immunosuppressive drugs used to maintain remission in inflammatory bowel diseases and in organ transplantation to reduce rejection. The increased cancer risk in organ transplant recipient has been known [...]

{ 0 comments }